MI-QSAR models for prediction of corneal permeability of organic compounds1
نویسندگان
چکیده
منابع مشابه
the application of multivariate probit models for conditional claim-types (the case study of iranian car insurance industry)
هدف اصلی نرخ گذاری بیمه ای تعیین نرخ عادلانه و منطقی از دیدگاه بیمه گر و بیمه گذار است. تعین نرخ یکی از مهم ترین مسایلی است که شرکتهای بیمه با آن روبرو هستند، زیرا تعیین نرخ اصلی ترین عامل در رقابت بین شرکتها است. برای تعیین حق بیمه ابتدا می باید مقدار مورد انتظار ادعای خسارت برای هر قرارداد بیمه را برآورد کرد. روش عمومی مدل سازی خسارتهای عملیاتی در نظر گرفتن تواتر و شدت خسارتها می باشد. اگر شر...
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Support vector regression for prediction of gas reservoirs permeability
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متن کاملReliable estimation of externally validated prediction errors for QSAR models
In most cases of QSAR modelling the final model used to make predictions, is not known a priori but has to be selected in a data driven fashion (e.g. selection of principal components, variable selection, selection of the best mathematical modelling technique). Reliable estimation of externally validated prediction errors under this model uncertainty is still a challenge in chemoinformatics. To...
متن کاملQSAR models for the prediction of plasma protein binding.
INTRODUCTION The prediction of plasma protein binding (ppb) is of paramount importance in the pharmacokinetics characterization of drugs, as it causes significant changes in volume of distribution, clearance and drug half life. This study utilized Quantitative Structure - Activity Relationships (QSAR) for the prediction of plasma protein binding. METHODS Protein binding values for 794 compoun...
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ژورنال
عنوان ژورنال: Acta Pharmacologica Sinica
سال: 2006
ISSN: 1671-4083,1745-7254
DOI: 10.1111/j.1745-7254.2006.00241.x